منابع مشابه
Long- and Short-Term Selective Forces on Malaria Parasite Genomes
Plasmodium parasites, the causal agents of malaria, result in more than 1 million deaths annually. Plasmodium are unicellular eukaryotes with small ∼23 Mb genomes encoding ∼5200 protein-coding genes. The protein-coding genes comprise about half of these genomes. Although evolutionary processes have a significant impact on malaria control, the selective pressures within Plasmodium genomes are po...
متن کاملPotent in vivo anti-malaria activity of Goniothalamin against rodent malaria parasite infection in mice
Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...
متن کاملPotent in vivo anti-malaria activity of Goniothalamin against rodent malaria parasite infection in mice
Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...
متن کاملMalaria Parasite Diagnostics
NIMR is a Referral Centre for Evaluating Commercially Developed Diagnostic Kits — Designated by the Drugs Controller General of India Fig. 1: PCR based diagnosis One of the most pronounced problems in controlling the morbidity and mortality caused by malaria is the limited access to effective diagnosis and treatment in areas where malaria is endemic. The most widely used routine method of micro...
متن کاملComplete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals.
Avian malaria parasites are prevalent around the world and infect a wide diversity of bird species. Here, we report the sequencing and analysis of high-quality draft genome sequences for two avian malaria species, Plasmodium relictum and Plasmodium gallinaceum We identify 50 genes that are specific to avian malaria, located in an otherwise conserved core of the genome that shares gene synteny w...
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ژورنال
عنوان ژورنال: Cell Host & Microbe
سال: 2017
ISSN: 1931-3128
DOI: 10.1016/j.chom.2017.02.019